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Charleston Voyage > Charleston Cruise Lines > American Cruise Line

American Cruises from Charleston

American Cruise Line offers small ship cruises on calm inland waterways. Sail south from Charleston on the Intracoastal Waterway and explore the beautiful towns and islands along the way.

American Cruise Line's ships hold less than 120 passengers and have the advantage of being small enough to visit interesting ports that big cruise ships cannot reach. Think of it as an American version of the river cruises that are so popular in Europe.

Watch the official video about Southeast Sea Islands cruises from Charleston.

American Cruise Line ships are modern and built in America, and crewed by Americans. Many staterooms have private balconies. The dining room seats all passengers at the same time. There are lounges for relaxing and socializing.

Learn all about the American Eagle ship that has cruises from Charleston.

Read American Cruise Lines cruise reviews.

2026

8-night Southeast Sea Islands cruises from Charleston, South Carolina. One-way to Amelia Island (Florida) with stops at Beaufort (South Carolina), Hilton Head Island (South Carolina), Savannah (Georgia), St Simons Island (Georgia) and Jekyll Island (Georgia).
• 2026 departures: February 6, February 13, February 20, February 27, March 6, March 13, March 20, March 25, March 27, April 3, April 8, April 10, April 17, April 22, May 1, May 6, May 15, October 31, November 14, November 16, November 21, November 24, November 30, December 5, December 8, December 14, December 19, December 22, December 28.

2027

8-night Southeast Sea Islands cruises from Charleston, South Carolina. One-way to Amelia Island (Florida) with stops at Beaufort (South Carolina), Hilton Head Island (South Carolina), Savannah (Georgia), St Simons Island (Georgia) and Jekyll Island (Georgia).
• 2027 departures: February 3, February 5, February 10, February 17, February 19, February 24, March 3, March 5, March 10, March 17, March 19, March 24, March 26, April 2, April 7, April 9, April 16, April 21, April 23, April 30, May 7, May 14, May 28, June 11, August 13, August 27, September 10, September 24, October 8, October 22, November 1, November 5, November 15, November 19, November 29, December 3, December 13, December 19, December 27.

Have fun. Explore America. Take an American Cruise Line cruise from Charleston.

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American Cruise outdoor deck
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